HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SNRK (Q9NRH2)
SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)
Gene: SNRK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 765
+	Hs
		227863 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MARK2_HUMAN (2-742): 8.32e-150: 458: 27.38
+	Hs
		226582 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MARK3_HUMAN (13-699): 5.14e-145: 445: 25.47
+	Hs
		226967 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		AAPK2_HUMAN (1-546): 4.85e-138: 420: 24.73
+	Sc
		419769 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		SNF1_YEAST (9-445): 3.04e-140: 428: 29.91
+	At
		1091641 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		KIN10_ARATH (1-420): 1.6e-150: 451: 32.81
+	At
		955189 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		KIN11_ARATH (1-425): 6.92e-150: 449: 32.07
+	Hs
		475524 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		AAPK2_HUMAN (1-546): 4.85e-138: 420: 24.73