HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32929329
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0098793 - presynapse
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 197
+	Hs
		227365 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SNTB2_HUMAN (61-179): 3e-32: 123: 35.25
+	Hs
		159120 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		227141 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		228125 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		228772 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		GOPC_HUMAN (92-173): 2.58e-13: 69.3: 46.34
+	Hs
		228384 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SNX27_HUMAN (91-175): 2.59e-12: 66.6: 38.14
+	Hs
		228116 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Dm
		677697 PRKN_DROME (1-463): 3.5e-106: 325: 42.19		DLG1_DROME (57-176): 1.06e-14: 73.6: 28.00
+	Hs
		159239 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		159293 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		1252454 HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		475714 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SNTB2_HUMAN (61-179): 3e-32: 123: 35.25
+	Hs
		159140 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		476217 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SNX27_HUMAN (91-175): 2.59e-12: 66.6: 38.14