HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: YTHD2 (Q9Y5A9)
YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)
Gene: YTHDF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32929329, 35509820, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 579
+	Hs
		228399 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		YTDC1_HUMAN (341-575): 6.57e-57: 205: 23.24
+	Hs
		228705 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		YTDC2_HUMAN (285-556): 1.53e-54: 202: 20.50
+	Hs
		226957 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SC24C_HUMAN (42-405): 4.03e-36: 146: 15.51
+	Hs
		228101 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KMT2C_HUMAN (7-383): 1.97e-13: 76.1: 14.92
+	Hs
		229228 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCLO_HUMAN (137-401): 1.11e-12: 73.5: 15.24
+	Hs
		226120 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SC31A_HUMAN (8-302): 1.84e-11: 69.2: 15.59
+	Hs
		302333 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		SC31A_HUMAN (8-302): 1.84e-11: 69.2: 15.59
+	Hs
		302245 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SC31A_HUMAN (8-302): 1.84e-11: 69.2: 15.59