HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RBM8A (Q9Y5S9)
RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A)
Gene: RBM8A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35987950, 24244333
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 174
+	Hs
		228645 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CSTFT_HUMAN (63-162): 1.63e-29: 115: 34.00
+	Hs
		226655 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CSTF2_HUMAN (63-162): 1.49e-28: 112: 34.00
+	Hs
		227533 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SF3B4_HUMAN (67-149): 3.35e-25: 101: 28.92
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (64-158): 1.19e-24: 101: 24.21
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (64-158): 2.06e-21: 91.8: 23.16
+	Hs
		227193 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIAR_HUMAN (66-164): 4.25e-20: 87.3: 20.20
+	Hs
		226635 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIA1_HUMAN (68-162): 8.55e-20: 86.8: 24.21
+	Hs
		227450 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		312493 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TIA1_HUMAN (68-162): 8.55e-20: 86.8: 24.21
+	Hs
		312605 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	At
		981214 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CP31A_ARATH (9-172): 4.05e-24: 97.6: 20.12
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (47-148): 1.32e-20: 89.5: 20.59
+	Hs
		475757 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	At
		983451 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP5_ARATH (71-156): 2.65e-18: 83: 22.09