Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: AUP1 (Q9Y679)
Lipid droplet-regulating VLDL assembly factor AUP1 (Ancient ubiquitous protein 1)
Gene: AUP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35256949
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CUE~ubiquitin
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0031624 - ubiquitin conjugating enzyme binding
GO:0031625 - ubiquitin protein ligase binding
GO:0036503 - ERAD pathway
GO:0043130 - ubiquitin binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 465
Hs

1 410
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024