HitPredict

Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 801
+	Hs
		631352 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		229407 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		229252 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		658677 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		243979 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		631414 CHD3_HUMAN (8-1052): 0: 801: 26.23		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		229455 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		KAT2A_HUMAN (293-452): 5.67e-30: 129: 24.38
+	Hs
		229505 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		BAZ1A_HUMAN (49-197): 1.07e-22: 106: 21.94
+	Mm
		291490 SMCA5_MOUSE (33-1052): 0: 1094: 98.33		BAZ1A_MOUSE (5-174): 6.19e-23: 107: 23.76
+	Hs
		229448 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		PHIP_HUMAN (76-730): 1.12e-13: 77.6: 11.21
+	Hs
		658742 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		BAZ1A_HUMAN (49-197): 1.07e-22: 106: 21.94
+	Hs
		244356 CHD3_HUMAN (8-1052): 0: 801: 26.23		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Dm
		1097647 ISWI_DROME (47-1051): 0: 977: 71.15		NU301_DROME (84-177): 1.14e-11: 70.9: 39.36
+	Hs
		998619 CHD3_HUMAN (8-1052): 0: 801: 26.23		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		319278 CHD5_HUMAN (5-1050): 0: 809: 26.28		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		319179 CHD3_HUMAN (8-1052): 0: 801: 26.23		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		1018704 CHD3_HUMAN (8-1052): 0: 801: 26.23		BAZ1A_HUMAN (49-197): 1.07e-22: 106: 21.94
+	Hs
		1018557 CHD3_HUMAN (8-1052): 0: 801: 26.23		PB1_HUMAN (306-773): 2.79e-18: 92.6: 12.33
+	Hs
		600135 CHD3_HUMAN (8-1052): 0: 801: 26.23		TAF1_HUMAN (64-263): 1.16e-16: 87.2: 16.00
+	Hs
		1255033 CHD5_HUMAN (5-1050): 0: 809: 26.28		PHIP_HUMAN (76-730): 1.12e-13: 77.6: 11.21