HitPredict

Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 538
+	Hs
		658643 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Dm
		853771 ISWI_DROME (47-1051): 0: 977: 71.15		IMA_DROME (3-538): 3.76e-121: 367: 43.60
+	Hs
		853580 CHD3_HUMAN (8-1052): 0: 801: 26.23		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		131423 CHD3_HUMAN (8-1052): 0: 801: 26.23		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91
+	Hs
		853257 CHD3_HUMAN (8-1052): 0: 801: 26.23		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		238679 CHD4_HUMAN (14-945): 0: 769: 26.95		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		853602 CHD4_HUMAN (14-945): 0: 769: 26.95		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		134899 CHD4_HUMAN (14-945): 0: 769: 26.95		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		238743 CHD8_HUMAN (6-1031): 0: 758: 26.13		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		168636 CHD4_HUMAN (14-945): 0: 769: 26.95		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Mm
		1000155 CHD8_MOUSE (6-1030): 0: 762: 26.24		IMA5_MOUSE (1-538): 1.75e-154: 453: 97.77
+	Hs
		853720 CHD8_HUMAN (6-1031): 0: 758: 26.13		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		134969 CHD8_HUMAN (6-1031): 0: 758: 26.13		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Sc
		744898 ISW1_YEAST (2-1046): 0: 790: 43.78		IMA1_YEAST (2-538): 8.07e-143: 424: 49.26
+	Mm
		192636 CHD8_MOUSE (6-1030): 0: 762: 26.24		IMA4_MOUSE (3-538): 1.37e-152: 448: 46.10
+	Hs
		853286 CHD4_HUMAN (14-945): 0: 769: 26.95		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		168673 CHD8_HUMAN (6-1031): 0: 758: 26.13		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Hs
		853480 CHD8_HUMAN (6-1031): 0: 758: 26.13		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Mm
		853539 CHD8_MOUSE (6-1030): 0: 762: 26.24		IMA1_MOUSE (3-538): 2.83e-147: 435: 44.18
+	Dm
		283986 CHDM_DROME (4-931): 0: 713: 27.96		O76522_DROME (4-538): 1.87e-146: 432: 44.49