HitPredict

Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: FOXG1 (P55316)
Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3)
Gene: FOXG1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 489
+	Hs
		658644 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		FOXG1_HUMAN (1-489): 9.66e-156: 453: 100.00
+	Hs
		229367 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		FOXK2_HUMAN (67-456): 6.09e-58: 204: 24.64
+	Hs
		229476 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		FOXC2_HUMAN (115-470): 1.92e-49: 178: 27.94
+	Hs
		229380 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		FOXC1_HUMAN (142-271): 2.43e-47: 173: 50.77
+	Hs
		229381 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		FOXL1_HUMAN (155-288): 2.31e-48: 171: 47.02
+	Hs
		229475 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		FOXB1_HUMAN (169-452): 7.39e-48: 169: 27.82
+	Hs
		126415 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		FOXE1_HUMAN (105-269): 1.08e-46: 168: 41.82
+	Hs
		208877 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		FOXS1_HUMAN (165-416): 5.89e-46: 164: 33.46
+	Hs
		658652 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		FOXK2_HUMAN (67-456): 6.09e-58: 204: 24.64
+	Hs
		877612 CHD4_HUMAN (14-945): 0: 769: 26.95		FOXG1_HUMAN (1-489): 9.66e-156: 453: 100.00
+	Hs
		658661 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		FOXC1_HUMAN (142-271): 2.43e-47: 173: 50.77
+	Hs
		658662 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		FOXL1_HUMAN (155-288): 2.31e-48: 171: 47.02
+	Hs
		126432 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		FOXE1_HUMAN (105-269): 1.08e-46: 168: 41.82
+	Hs
		877716 CHD3_HUMAN (8-1052): 0: 801: 26.23		FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84
+	Hs
		964181 CHD4_HUMAN (14-945): 0: 769: 26.95		FOXK2_HUMAN (67-456): 6.09e-58: 204: 24.64
+	Hs
		1021365 CHD7_HUMAN (9-1049): 0: 800: 25.86		FOXL1_HUMAN (155-288): 2.31e-48: 171: 47.02
+	Hs
		877733 CHD4_HUMAN (14-945): 0: 769: 26.95		FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84
+	Hs
		1021109 CHD4_HUMAN (14-945): 0: 769: 26.95		FOXC1_HUMAN (142-271): 2.43e-47: 173: 50.77
+	Hs
		126461 CHD4_HUMAN (14-945): 0: 769: 26.95		FOXE1_HUMAN (105-269): 1.08e-46: 168: 41.82
+	Mm
		725295 SMCA4_MOUSE (63-936): 0: 725: 30.53		FOXA2_MOUSE (81-381): 3.85e-48: 174: 27.24