HitPredict

Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 136
+	Hs
		229359 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Mm
		935460 SMCA5_MOUSE (33-1052): 0: 1094: 98.33		H31_MOUSE (1-136): 3.08e-60: 183: 96.32
+	Mm
		952763 SMCA5_MOUSE (33-1052): 0: 1094: 98.33		H33_MOUSE (1-136): 1.12e-59: 182: 100.00
+	Mm
		952266 SMCA5_MOUSE (33-1052): 0: 1094: 98.33		H32_MOUSE (1-136): 5.32e-59: 180: 97.06
+	Hs
		229341 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		658647 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		658651 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		658641 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Sc
		902117 ISW2_YEAST (1-1052): 0: 848: 45.67		H3_YEAST (1-136): 3.62e-54: 168: 90.44
+	Mm
		56901 CHD5_MOUSE (5-1050): 0: 810: 26.45		H33_MOUSE (1-136): 1.12e-59: 182: 100.00
+	Hs
		935016 CHD5_HUMAN (5-1050): 0: 809: 26.28		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		1086233 CHD5_HUMAN (5-1050): 0: 809: 26.28		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		934705 CHD3_HUMAN (8-1052): 0: 801: 26.23		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		935324 CHD7_HUMAN (9-1049): 0: 800: 25.86		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952302 CHD3_HUMAN (8-1052): 0: 801: 26.23		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		952670 CHD7_HUMAN (9-1049): 0: 800: 25.86		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Sc
		744893 ISW1_YEAST (2-1046): 0: 790: 43.78		H3_YEAST (1-136): 3.62e-54: 168: 90.44
+	Hs
		934770 CHD4_HUMAN (14-945): 0: 769: 26.95		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		828213 CHD3_HUMAN (8-1052): 0: 801: 26.23		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		828410 CHD7_HUMAN (9-1049): 0: 800: 25.86		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76