HitPredict

Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0016589 - NURF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 601
+	Hs
		658748 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		HMGX4_HUMAN (1-601): 0: 813: 100.00
+	Hs
		1255050 CHD5_HUMAN (5-1050): 0: 809: 26.28		HMGX4_HUMAN (1-601): 0: 813: 100.00
+	Hs
		1018734 CHD3_HUMAN (8-1052): 0: 801: 26.23		HMGX4_HUMAN (1-601): 0: 813: 100.00
+	Hs
		229339 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Hs
		229376 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Mm
		1142014 SMCA5_MOUSE (33-1052): 0: 1094: 98.33		Q60I23_MOUSE (375-551): 4.16e-32: 128: 15.82
+	Hs
		229284 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		229467 SMCA5_HUMAN (19-1052): 0: 1097: 100.00		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		658657 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		449557 SMCA1_HUMAN (71-1030): 0: 1042: 85.29		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Zm
		9144 A0A1D6FIP6_MAIZE (9-1052): 0: 921: 50.57		A0A1D6EUM9_MAIZE (390-506): 6.75e-15: 74.9: 18.03
+	Sc
		705912 ISW2_YEAST (1-1052): 0: 848: 45.67		IXR1_YEAST (316-512): 2.11e-35: 143: 16.81
+	Hs
		1018557 CHD3_HUMAN (8-1052): 0: 801: 26.23		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		727856 CHD3_HUMAN (8-1052): 0: 801: 26.23		SOX6_HUMAN (320-556): 1.34e-33: 138: 17.05
+	Mm
		57186 CHD7_MOUSE (9-1051): 0: 806: 25.90		Q60I23_MOUSE (375-551): 4.16e-32: 128: 15.82
+	Hs
		225761 CHD5_HUMAN (5-1050): 0: 809: 26.28		SOX15_HUMAN (363-554): 8.83e-31: 122: 14.49
+	Hs
		817986 CHD3_HUMAN (8-1052): 0: 801: 26.23		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Hs
		996636 CHD3_HUMAN (8-1052): 0: 801: 26.23		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Sc
		514275 ISW2_YEAST (1-1052): 0: 848: 45.67		NHP6B_YEAST (388-479): 1.39e-15: 74.5: 28.72
+	Sc
		514218 ISW2_YEAST (1-1052): 0: 848: 45.67		NHP6A_YEAST (394-476): 2.15e-14: 71: 29.41