HitPredict

Interactor 1: JIP4 (O60271)
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)
Gene: SPAG9

Interactor 2: JIP4 (O60271)
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)
Gene: SPAG9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 37071682, 19644450
Identification Methods cross-linking study, cosedimentation in solution
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains JIP_LZII~JIP_LZII, WD40_2~WD40_2
Common GO terms GO:0001669 - acrosomal vesicle
GO:0001933 - negative regulation of protein phosphorylation
GO:0005078 - MAP-kinase scaffold activity
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
and 16 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1321
Hs

1 1321
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024