HitPredict

Interactor 1: JIP4 (O60271)
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)
Gene: SPAG9

Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	14743216, 27609421, 35140242, 25609649
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1321 Hs			1 968
+	Mm
		103601 JIP4_MOUSE (1-1321): 0: 799: 96.52		ANK3_MOUSE (381-967): 1e-99: 346: 14.24
+	Mm
		103611 JIP3_MOUSE (1-1321): 0: 704: 55.14		ANK3_MOUSE (381-967): 1e-99: 346: 14.24
+	Hs
		229666 JIP4_HUMAN (1-1321): 0: 803: 100.00		ANK3_HUMAN (843-967): 8.76e-09: 61.9: 12.40
+	Hs
		725142 MYH10_HUMAN (500-978): 2.95e-13: 77.2: 8.75		TF65_HUMAN (28-420): 6.77e-116: 368: 34.41
+	Hs
		724782 MYH9_HUMAN (437-932): 1.04e-14: 81.8: 9.68		ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37
+	Hs
		725139 MYH10_HUMAN (500-978): 2.95e-13: 77.2: 8.75		ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37
+	Hs
		724779 MYH9_HUMAN (437-932): 1.04e-14: 81.8: 9.68		NFKB2_HUMAN (701-942): 4.27e-26: 117: 14.23