HitPredict

Interactor 1: JIP4 (O60271)
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)
Gene: SPAG9

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1321 Hs			1 360
+	Mm
		926440 JIP3_MOUSE (1-1321): 0: 704: 55.14		MK01_MOUSE (10-360): 4.96e-158: 449: 99.72
+	Hs
		229677 JIP4_HUMAN (1-1321): 0: 803: 100.00		MK14_HUMAN (18-356): 7.86e-112: 332: 48.97
+	Mm
		814047 JIP4_MOUSE (1-1321): 0: 799: 96.52		MK14_MOUSE (18-356): 3.49e-111: 330: 48.97
+	Rn
		926486 ROCK2_RAT (276-759): 2.08e-20: 100: 11.99		MK01_RAT (10-360): 4.96e-158: 449: 99.72