HitPredict

Interactor 1: JIP4 (O60271)
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)
Gene: SPAG9

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26831064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1321 Hs			1 1863
+	Hs
		148473 CTRO_HUMAN (310-776): 4.58e-19: 96.1: 11.60		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		724691 MYH9_HUMAN (437-932): 1.04e-14: 81.8: 9.68		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		725099 MYH10_HUMAN (500-978): 2.95e-13: 77.2: 8.75		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		528393 MYH6_HUMAN (358-966): 2.92e-21: 103: 9.02		TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54
+	Hs
		522639 MYH7_HUMAN (382-959): 3.66e-20: 99.9: 9.76		TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54
+	Hs
		149258 CTRO_HUMAN (310-776): 4.58e-19: 96.1: 11.60		TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52
+	Hs
		725005 MYH9_HUMAN (437-932): 1.04e-14: 81.8: 9.68		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30
+	Hs
		725238 MYH10_HUMAN (500-978): 2.95e-13: 77.2: 8.75		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30
+	Mm
		1093546 MYH9_MOUSE (533-967): 1.61e-10: 68.3: 7.82		TRI72_MOUSE (18-91): 9.41e-12: 71.5: 30.26