HitPredict

Interactor 1: KIF5C (O60282)
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)
Gene: KIF5C

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.50	0.656

Property	Details
Experiments	17353931, 33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 247
+	Hs
		855623 KIF11_HUMAN (8-866): 2.09e-162: 505: 27.69		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		909493 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		702835 KIF5A_MOUSE (2-956): 4.12e-138: 441: 74.14		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		904501 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		981963 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		855614 KIF11_HUMAN (8-866): 2.09e-162: 505: 27.69		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		229853 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		910062 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		905150 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		683303 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		926981 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646844 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		229841 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		229850 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Mm
		659991 KIF5C_MOUSE (1-957): 1.27e-128: 414: 98.12		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		229840 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683742 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927565 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647306 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		684344 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16