HitPredict

Interactor 1: KIF5C (O60282)
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)
Gene: KIF5C

Interactor 2: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008017 - microtubule binding GO:0051028 - mRNA transport
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 632
+	Hs
		988845 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Mm
		702832 KIF5A_MOUSE (2-956): 4.12e-138: 441: 74.14		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Hs
		231504 KIF1B_HUMAN (5-747): 2.93e-109: 374: 23.29		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Mm
		659989 KIF5C_MOUSE (1-957): 1.27e-128: 414: 98.12		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Hs
		166370 KIF3B_HUMAN (8-334): 3.14e-61: 224: 45.88		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		989212 KIF3A_HUMAN (598-830): 6.23e-10: 65.2: 10.73		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		702890 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Mm
		729600 KI21B_MOUSE (244-862): 6.02e-11: 69.1: 10.02		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Mm
		702844 KIF5A_MOUSE (2-956): 4.12e-138: 441: 74.14		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Mm
		729494 KINH_MOUSE (672-957): 8.12e-09: 61.7: 10.11		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Mm
		660000 KIF5C_MOUSE (1-957): 1.27e-128: 414: 98.12		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Hs
		843943 KIF17_HUMAN (5-451): 3.21e-98: 333: 35.14		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Mm
		1207103 KI21B_MOUSE (244-862): 6.02e-11: 69.1: 10.02		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Mm
		1143113 KINH_MOUSE (672-957): 8.12e-09: 61.7: 10.11		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Mm
		1142909 KI21A_MOUSE (477-949): 1.73e-19: 96.8: 12.24		FXR1_MOUSE (1-334): 0: 596: 73.65
+	Hs
		844029 KIF1A_HUMAN (5-677): 2.15e-108: 371: 24.22		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56