HitPredict

Interactor 1: KIF5C (O60282)
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)
Gene: KIF5C

Interactor 2: KLC1 (Q07866)
Kinesin light chain 1 (KLC 1)
Gene: KLC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 9624122, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005871 - kinesin complex GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 573
+	Hs
		992334 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		KLC1_HUMAN (1-573): 2.46e-113: 350: 100.00
+	Mm
		702846 KIF5A_MOUSE (2-956): 4.12e-138: 441: 74.14		Q8CD76_MOUSE (1-571): 1.06e-113: 353: 95.10
+	Hs
		1017559 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43
+	Hs
		229891 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		KLC4_HUMAN (5-571): 4.27e-99: 315: 68.53
+	Hs
		229887 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43
+	Hs
		1017539 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65
+	Hs
		229869 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65
+	Mm
		660001 KIF5C_MOUSE (1-957): 1.27e-128: 414: 98.12		KLC3_MOUSE (356-571): 1.05e-13: 75.8: 17.41
+	Hs
		231604 KIF1B_HUMAN (5-747): 2.93e-109: 374: 23.29		TMTC1_HUMAN (336-566): 2.77e-18: 90.8: 15.88
+	Hs
		1160005 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65
+	Hs
		702891 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		KLC1_HUMAN (1-573): 2.46e-113: 350: 100.00
+	Hs
		702974 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43
+	Hs
		253263 KI21B_HUMAN (585-957): 5.52e-10: 65.6: 9.78		TMTC3_HUMAN (184-572): 1.42e-31: 132: 12.76
+	Ce
		712252 KINH_CAEEL (454-915): 3.96e-17: 88.7: 21.52		KLC_CAEEL (336-573): 3.18e-22: 102: 21.67
+	Ce
		712255 KINH_CAEEL (454-915): 3.96e-17: 88.7: 21.52		Q21592_CAEEL (312-571): 4.83e-16: 83.1: 15.91
+	Dm
		566087 KINH_DROME (506-956): 6.11e-11: 68.7: 10.04		KLC_DROME (325-567): 2.72e-19: 93.2: 19.59
+	Hs
		101750 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		F8W6L3_HUMAN (336-567): 8.43e-21: 98.2: 21.25
+	Dm
		115868 KINH_DROME (506-956): 6.11e-11: 68.7: 10.04		M9PGT5_DROME (212-499): 1.6e-14: 78.8: 16.01
+	Hs
		702921 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65
+	Hs
		174664 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		OGT1_HUMAN (382-531): 4.66e-12: 71.2: 13.33