HitPredict

Interactor 1: KIF5C (O60282)
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)
Gene: KIF5C

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 1374
+	Hs
		229875 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		609221 KIF11_HUMAN (8-866): 2.09e-162: 505: 27.69		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		412097 KIF11_HUMAN (8-866): 2.09e-162: 505: 27.69		FYN_HUMAN (104-408): 1.36e-104: 344: 30.07
+	Hs
		229833 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		702941 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		384537 KIF11_HUMAN (8-866): 2.09e-162: 505: 27.69		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		411368 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		INSR_HUMAN (111-395): 4.12e-41: 167: 36.27
+	Hs
		229829 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		385569 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384730 KIF1A_HUMAN (5-677): 2.15e-108: 371: 24.22		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		435756 KI13A_HUMAN (5-766): 3.9e-101: 350: 23.96		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Mm
		222885 KI21B_MOUSE (244-862): 6.02e-11: 69.1: 10.02		ACK1_MOUSE (55-976): 4.88e-124: 413: 20.25
+	Mm
		546301 KINH_MOUSE (672-957): 8.12e-09: 61.7: 10.11		NTRK2_MOUSE (30-400): 1.89e-106: 359: 28.03
+	Hs
		166354 KIF3B_HUMAN (8-334): 3.14e-61: 224: 45.88		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		309273 KIF4A_HUMAN (303-753): 3.06e-10: 66.7: 12.04		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		385083 KI21A_HUMAN (254-872): 8.4e-10: 65.2: 10.47		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		385776 KIF3A_HUMAN (598-830): 6.23e-10: 65.2: 10.73		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384364 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77