HitPredict

Interactor 1: KIF5C (O60282)
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)
Gene: KIF5C

Interactor 2: KLC2 (Q9H0B6)
Kinesin light chain 2 (KLC 2)
Gene: KLC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	9624122, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005871 - kinesin complex GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 622
+	Hs
		1017559 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		KLC2_HUMAN (1-622): 1.59e-128: 393: 100.00
+	Mm
		702846 KIF5A_MOUSE (2-956): 4.12e-138: 441: 74.14		Q8CD76_MOUSE (1-593): 7.15e-105: 332: 67.71
+	Hs
		229891 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Hs
		231604 KIF1B_HUMAN (5-747): 2.93e-109: 374: 23.29		TMTC1_HUMAN (73-507): 1.74e-41: 163: 13.79
+	Hs
		1017539 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		150089 KIF1C_HUMAN (5-707): 2.58e-95: 327: 23.49		UTY_HUMAN (126-599): 3.47e-48: 184: 13.94
+	Hs
		992334 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		229869 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Mm
		660001 KIF5C_MOUSE (1-957): 1.27e-128: 414: 98.12		KLC3_MOUSE (363-617): 9.36e-17: 85.5: 22.08
+	Hs
		229856 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		1160005 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Dm
		115868 KINH_DROME (506-956): 6.11e-11: 68.7: 10.04		M9PGT5_DROME (42-525): 1.75e-59: 212: 15.79
+	Hs
		174664 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	Ce
		712252 KINH_CAEEL (454-915): 3.96e-17: 88.7: 21.52		KLC_CAEEL (312-620): 1.61e-24: 109: 17.35
+	Dm
		566087 KINH_DROME (506-956): 6.11e-11: 68.7: 10.04		KLC_DROME (268-594): 1.89e-28: 121: 26.06
+	Hs
		253263 KI21B_HUMAN (585-957): 5.52e-10: 65.6: 9.78		TMTC3_HUMAN (7-407): 5.25e-22: 103: 13.96
+	Ce
		712255 KINH_CAEEL (454-915): 3.96e-17: 88.7: 21.52		Q21592_CAEEL (406-583): 9.87e-11: 66.6: 9.79
+	Hs
		702921 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		702891 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		101750 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		F8W6L3_HUMAN (406-586): 1.16e-09: 63.2: 12.50