HitPredict

Interactor 1: KIF5C (O60282)
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)
Gene: KIF5C

Interactor 2: TRAK1 (Q9UPV9)
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
Gene: TRAK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15644324
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044295 - axonal growth cone GO:1904115 - axon cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 953
+	Hs
		1017567 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		TRAK1_HUMAN (1-953): 0: 646: 100.00
+	Hs
		230500 KIF5A_HUMAN (2-956): 5.34e-140: 446: 74.45		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Rn
		1163333 KIF5A_RAT (2-956): 6.95e-138: 440: 73.72		TRAK2_RAT (30-938): 1.34e-94: 321: 45.91
+	Hs
		229823 KIF5C_HUMAN (1-957): 7.99e-130: 417: 100.00		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Hs
		702995 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		TRAK1_HUMAN (1-953): 0: 646: 100.00
+	Hs
		230481 KIF1B_HUMAN (5-747): 2.93e-109: 374: 23.29		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Hs
		148562 KIF11_HUMAN (8-866): 2.09e-162: 505: 27.69		CTRO_HUMAN (33-527): 4.9e-19: 95.4: 11.83
+	Mm
		193275 KIF5A_MOUSE (2-956): 4.12e-138: 441: 74.14		HAP1_MOUSE (91-524): 2.23e-27: 120: 23.80
+	Hs
		725033 KI13B_HUMAN (6-762): 9.83e-112: 381: 23.11		MYH9_HUMAN (195-661): 7.37e-17: 88.3: 10.53
+	Hs
		230487 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Rn
		1102446 KINH_RAT (688-957): 7.39e-09: 61.7: 9.69		TRAK2_RAT (30-938): 1.34e-94: 321: 45.91
+	Rn
		869341 KIF5C_RAT (591-957): 2.87e-12: 72.9: 12.50		HAP1_RAT (91-524): 3.53e-28: 123: 23.20
+	Rn
		869352 KINH_RAT (688-957): 7.39e-09: 61.7: 9.69		HAP1_RAT (91-524): 3.53e-28: 123: 23.20
+	Hs
		702999 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		MYO5A_HUMAN (47-567): 2.47e-18: 93.1: 11.22
+	Hs
		253264 KI21A_HUMAN (254-872): 8.4e-10: 65.2: 10.47		KI21B_HUMAN (22-544): 4.05e-14: 79.1: 8.35
+	Dm
		566098 KINH_DROME (506-956): 6.11e-11: 68.7: 10.04		MILT_DROME (258-522): 2.53e-09: 63.3: 10.94
+	Hs
		87354 KINH_HUMAN (688-957): 5.26e-09: 62.5: 10.04		C9JC32_HUMAN (17-258): 3.88e-10: 66: 10.66