HitPredict

Interactor 1: MGRN1 (O60291)
E3 ubiquitin-protein ligase MGRN1 (EC 2.3.2.27) (Mahogunin RING finger protein 1) (RING finger protein 156) (RING-type E3 ubiquitin transferase MGRN1)
Gene: MGRN1

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 158
+	Hs
		230183 MGRN1_HUMAN (1-552): 0: 894: 100.00		UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42
+	Hs
		230126 MGRN1_HUMAN (1-552): 0: 894: 100.00		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		230132 MGRN1_HUMAN (1-552): 0: 894: 100.00		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		230131 MGRN1_HUMAN (1-552): 0: 894: 100.00		UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07
+	Hs
		230127 MGRN1_HUMAN (1-552): 0: 894: 100.00		UB2E1_HUMAN (3-156): 7.23e-67: 203: 33.12
+	At
		715118 LUL3_ARATH (25-327): 2.64e-113: 343: 33.76		UBC8_ARATH (4-157): 5.54e-74: 219: 35.71
+	At
		1195870 LUL3_ARATH (25-327): 2.64e-113: 343: 33.76		UBC29_ARATH (4-156): 2.89e-71: 212: 35.95