HitPredict

Interactor 1: SI1L3 (O60292)
Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3)
Gene: SIPA1L3

Interactor 2: LZTS3 (O60299)
Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1)
Gene: LZTS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1781 Hs			1 673
+	Hs
		230555 SI1L2_HUMAN (1-1774): 0: 1393: 43.94		LZTS3_HUMAN (1-673): 7.26e-72: 247: 100.00
+	Hs
		165788 SI1L2_HUMAN (1-1774): 0: 1393: 43.94		N4BP3_HUMAN (169-652): 1.44e-45: 172: 27.26
+	Hs
		1350316 SI1L2_HUMAN (1-1774): 0: 1393: 43.94		LZTS1_HUMAN (97-655): 5.21e-28: 121: 34.46
+	Hs
		1310197 SI1L2_HUMAN (1-1774): 0: 1393: 43.94		LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04
+	Hs
		230273 SI1L3_HUMAN (1-1781): 0: 1374: 100.00		LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04
+	Hs
		196381 SI1L1_HUMAN (3-1774): 0: 1211: 45.79		LZTS3_HUMAN (1-673): 7.26e-72: 247: 100.00
+	Hs
		230212 SI1L3_HUMAN (1-1781): 0: 1374: 100.00		MYH9_HUMAN (323-628): 1.38e-09: 63.9: 14.06
+	Hs
		196501 SI1L1_HUMAN (3-1774): 0: 1211: 45.79		LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04
+	Hs
		196494 SI1L1_HUMAN (3-1774): 0: 1211: 45.79		CEP63_HUMAN (318-640): 4.94e-12: 71.1: 16.77
+	Hs
		835080 TSC2_HUMAN (227-876): 3.86e-138: 474: 15.77		ANR35_HUMAN (71-671): 5.62e-28: 122: 15.05
+	Hs
		1151774 RGPA1_HUMAN (327-850): 4.76e-106: 379: 18.68		CEP63_HUMAN (318-640): 4.94e-12: 71.1: 16.77
+	Hs
		1310230 MAST1_HUMAN (986-1524): 1.08e-41: 171: 14.29		LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04
+	Hs
		1291406 SIPA1_HUMAN (1448-1781): 4.85e-14: 80.2: 19.42		LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04
+	Hs
		1255127 DLG5_HUMAN (1042-1430): 3.08e-09: 64.4: 9.23		LZTS2_HUMAN (116-657): 2.79e-23: 106: 30.04
+	Hs
		724961 SIPA1_HUMAN (1448-1781): 4.85e-14: 80.2: 19.42		MYH9_HUMAN (323-628): 1.38e-09: 63.9: 14.06
+	Hs
		1255124 DLG5_HUMAN (1042-1430): 3.08e-09: 64.4: 9.23		CEP63_HUMAN (318-640): 4.94e-12: 71.1: 16.77