HitPredict

Interactor 1: SI1L3 (O60292)
Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3)
Gene: SIPA1L3

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1781 Hs			1 255
+	Hs
		910116 SI1L2_HUMAN (1-1774): 0: 1393: 43.94		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		196427 SI1L1_HUMAN (3-1774): 0: 1211: 45.79		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		835035 TSC2_HUMAN (227-876): 3.86e-138: 474: 15.77		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909669 RPGP2_HUMAN (350-891): 3.05e-128: 421: 28.52		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Dm
		114606 M9PD17_DROME (96-834): 4.01e-124: 434: 15.96		1433E_DROME (1-254): 2.95e-146: 411: 82.69
+	Dm
		955043 Q9VW83_DROME (96-834): 4.1e-124: 434: 15.96		1433E_DROME (1-254): 2.95e-146: 411: 82.69
+	Hs
		909678 RGPA1_HUMAN (327-850): 4.76e-106: 379: 18.68		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		812874 RPGP1_HUMAN (401-842): 1.03e-112: 375: 31.01		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910182 MAST1_HUMAN (986-1524): 1.08e-41: 171: 14.29		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		297821 K0754_HUMAN (983-1458): 5.9e-32: 139: 10.74		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909712 OTOG_HUMAN (1215-1732): 7.91e-28: 125: 10.17		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909845 DLG5_HUMAN (1042-1430): 3.08e-09: 64.4: 9.23		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00