Interactor 1: CREB3 (O43889)
Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)]
Gene: CREB3
Interactor 2: PTC1 (Q13635)
Protein patched homolog 1 (PTC) (PTC1)
Gene: PTCH1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 0.60 | 0.560 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25910212 |
| Identification Methods | two hybrid, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0045893 - positive regulation of DNA-templated transcription |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
