HitPredict

Interactor 1: ZEB2 (O60315)
Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b)
Gene: ZEB2

Interactor 2: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	34026424, 18182442, 26028330
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1214 Hs			1 668
+	Hs
		231234 ZEB2_HUMAN (1-1214): 7.66e-177: 556: 83.52		MTA1_HUMAN (1-668): 0: 704: 56.24
+	Hs
		231262 ZEB2_HUMAN (1-1214): 7.66e-177: 556: 83.52		RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27
+	Hs
		1238812 ZN383_HUMAN (290-608): 3.89e-36: 145: 14.33		RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62
+	Hs
		271801 PRDM1_HUMAN (174-302): 3.7e-22: 105: 19.38		RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62
+	Hs
		271804 PRDM1_HUMAN (174-302): 3.7e-22: 105: 19.38		RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27