HitPredict

Interactor 1: ZEB2 (O60315)
Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b)
Gene: ZEB2

Interactor 2: MTA1 (Q13330)
Metastasis-associated protein MTA1
Gene: MTA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.684

Property	Details
Experiments	34026424, 18182442, 26028330
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, chromatin immunoprecipitation assay
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1214 Hs			1 715
+	Hs
		231188 ZEB2_HUMAN (1-1214): 7.66e-177: 556: 83.52		MTA2_HUMAN (1-715): 0: 741: 57.55
+	Hs
		231262 ZEB2_HUMAN (1-1214): 7.66e-177: 556: 83.52		RCOR1_HUMAN (165-532): 5.9e-67: 230: 18.60
+	Hs
		1238812 ZN383_HUMAN (290-608): 3.89e-36: 145: 14.33		RCOR3_HUMAN (167-532): 3.91e-75: 252: 17.71
+	Hs
		271801 PRDM1_HUMAN (174-302): 3.7e-22: 105: 19.38		RCOR3_HUMAN (167-532): 3.91e-75: 252: 17.71
+	Hs
		271804 PRDM1_HUMAN (174-302): 3.7e-22: 105: 19.38		RCOR1_HUMAN (165-532): 5.9e-67: 230: 18.60