HitPredict

Interactor 1: PCDGC (O60330)
Protocadherin gamma-A12 (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin-3)
Gene: PCDHGA12

Interactor 2: RYK (P34925)
Tyrosine-protein kinase RYK (EC 2.7.10.1)
Gene: RYK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 932 Hs			1 607
+	Hs
		713898 PCDG6_HUMAN (1-917): 0: 1114: 74.48		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713899 PCDG5_HUMAN (1-917): 0: 1106: 74.16		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713897 PCDG7_HUMAN (1-917): 0: 1099: 74.37		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713900 PCDGB_HUMAN (1-917): 0: 1094: 75.33		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713896 PCDGH_HUMAN (2-917): 0: 1071: 52.62		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		523229 PCDG5_HUMAN (1-917): 0: 1106: 74.16		SRC_HUMAN (315-602): 2.06e-108: 338: 30.80
+	Hs
		508295 PCDA8_HUMAN (1-905): 0: 974: 38.52		FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29
+	Hs
		713894 PCDB2_HUMAN (13-773): 0: 602: 45.23		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713884 PCD10_HUMAN (18-902): 0: 596: 38.90		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		508294 PCDB7_HUMAN (4-789): 0: 592: 43.98		FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29
+	Hs
		385795 PCDB3_HUMAN (5-773): 0: 603: 45.02		NTRK1_HUMAN (122-607): 2.22e-129: 400: 25.65
+	Hs
		433517 PCDB3_HUMAN (5-773): 0: 603: 45.02		YES_HUMAN (315-602): 3.09e-108: 337: 31.14
+	Hs
		523182 PCD10_HUMAN (18-902): 0: 596: 38.90		SRC_HUMAN (315-602): 2.06e-108: 338: 30.80
+	Hs
		674578 PCDB3_HUMAN (5-773): 0: 603: 45.02		UFO_HUMAN (315-603): 3.55e-55: 203: 37.63
+	Hs
		713888 PCDGK_HUMAN (2-443): 4.84e-93: 317: 24.89		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		713895 PCDGL_HUMAN (2-443): 4.68e-88: 303: 25.00		RYK_HUMAN (1-607): 1.73e-146: 438: 100.00
+	Hs
		385714 PCDGK_HUMAN (2-443): 4.84e-93: 317: 24.89		NTRK1_HUMAN (122-607): 2.22e-129: 400: 25.65
+	Hs
		523204 PCDGK_HUMAN (2-443): 4.84e-93: 317: 24.89		SRC_HUMAN (315-602): 2.06e-108: 338: 30.80
+	Hs
		433505 PCDGK_HUMAN (2-443): 4.84e-93: 317: 24.89		YES_HUMAN (315-602): 3.09e-108: 337: 31.14
+	Mm
		555033 PCDAA_MOUSE (2-241): 6.78e-30: 130: 19.92		MET_MOUSE (330-593): 4.01e-59: 216: 39.47