HitPredict

Interactor 1: KIF1B (O60333)
Kinesin-like protein KIF1B (Klp)
Gene: KIF1B

Interactor 2: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	1.00	0.653

Property	Details
Experiments	12097473
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~KIF1B, PH~SH3_1
Common GO terms	GO:0008021 - synaptic vesicle GO:0043005 - neuron projection
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1816 Hs			1 724
+	Rn
		292059 KIF1B_RAT (1-1816): 0: 1809: 96.81		DLG4_RAT (1-724): 0: 668: 99.86
+	Hs
		231517 KIF1B_HUMAN (1-1816): 0: 1838: 100.00		SCRIB_HUMAN (58-243): 6.07e-25: 113: 40.72
+	Hs
		231509 KIF1B_HUMAN (1-1816): 0: 1838: 100.00		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93
+	Hs
		231550 KIF1B_HUMAN (1-1816): 0: 1838: 100.00		MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50
+	Hs
		159121 KIF1B_HUMAN (1-1816): 0: 1838: 100.00		CSKP_HUMAN (6-200): 2.34e-19: 95.2: 14.29
+	Rn
		292061 KIF1B_RAT (1-1816): 0: 1809: 96.81		DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97
+	Ce
		619838 UN104_CAEEL (4-1803): 0: 1302: 40.70		LIN2_CAEEL (80-719): 2.76e-103: 340: 20.21
+	Mm
		702841 KIF5A_MOUSE (652-1109): 4.53e-17: 89.9: 9.40		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Mm
		93501 E9Q4K7_MOUSE (711-1041): 7.92e-17: 89.5: 14.76		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Hs
		942384 KI13B_HUMAN (772-1041): 1.92e-15: 84.9: 15.87		DLG4_HUMAN (1-724): 0: 667: 100.00
+	Mm
		660025 KIF3A_MOUSE (667-902): 4.54e-09: 63.3: 10.17		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Hs
		1049953 KIF14_HUMAN (1-877): 0: 604: 31.96		SCRIB_HUMAN (58-243): 6.07e-25: 113: 40.72
+	Hs
		1021494 KIF14_HUMAN (1-877): 0: 604: 31.96		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93
+	Hs
		1066234 KIF14_HUMAN (1-877): 0: 604: 31.96		MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50
+	Hs
		1066390 KIF14_HUMAN (1-877): 0: 604: 31.96		PALS1_HUMAN (3-238): 7.09e-18: 90.2: 12.30
+	Dm
		54780 A1ZA18_DROME (455-965): 9.27e-101: 362: 25.09		DLG1_DROME (194-394): 7.51e-09: 61.3: 18.10
+	Hs
		159161 KINH_HUMAN (701-1149): 2.74e-16: 87.2: 9.11		CSKP_HUMAN (6-200): 2.34e-19: 95.2: 14.29
+	Hs
		1021567 KI13B_HUMAN (772-1041): 1.92e-15: 84.9: 15.87		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93