HitPredict

Interactor 1: KIF1B (O60333)
Kinesin-like protein KIF1B (Klp)
Gene: KIF1B

Interactor 2: KIF1A (Q12756)
Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104)
Gene: KIF1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.866

The method score is based on:

Property Details
Experiments 28514442, 33961781, 32814053
Identification Methods affinity chromatography technology, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FHA~FHA, FHA~Kinesin_assoc, FHA~PH, Kinesin~Kinesin, Kinesin~Kinesin_assoc, Kinesin_assoc~Kinesin_assoc, PH~PH
Common GO terms GO:0005524 - ATP binding
GO:0005871 - kinesin complex
GO:0005874 - microtubule
GO:0007018 - microtubule-based movement
GO:0008017 - microtubule binding
and 8 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1816
Hs

1 1690
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024