HitPredict

Interactor 1: MARH6 (O60337)
E3 ubiquitin-protein ligase MARCHF6 (EC 2.3.2.27) (Doa10 homolog) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI) (Protein TEB-4) (RING finger protein 176) (RING-type E3 ubiquitin transferase MARCHF6)
Gene: MARCHF6

Interactor 2: MARH6 (O60337)
E3 ubiquitin-protein ligase MARCHF6 (EC 2.3.2.27) (Doa10 homolog) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI) (Protein TEB-4) (RING finger protein 176) (RING-type E3 ubiquitin transferase MARCHF6)
Gene: MARCHF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.626

The method score is based on:

Property Details
Experiments 17848550, 35941365
Identification Methods enzymatic study, two hybrid, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000835 - ER ubiquitin ligase complex
GO:0004842 - ubiquitin-protein transferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0008270 - zinc ion binding
and 10 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 910
Hs

1 910
+ Hs
+ Zm
+ Hs
+ Hs
+ Hs
+ Rn
+ Sc
+ Hs
+ Zm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024