Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 12493763, 34709266, 21937684, 23455924, 36321378
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Amino_oxidase~Amino_oxidase, Amino_oxidase~SWIRM, SWIRM~SWIRM
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0002039 - p53 binding
GO:0002052 - positive regulation of neuroblast proliferation
and 51 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 852
Hs

1 852
+ Mm
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024