HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23455924
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0021987 - cerebral cortex development GO:0030374 - nuclear receptor coactivator activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 805
+	Hs
		232618 KDM1A_HUMAN (1-852): 0: 936: 100.00		TACC3_HUMAN (35-803): 1.31e-42: 168: 22.72
+	Hs
		232112 KDM1A_HUMAN (1-852): 0: 936: 100.00		DYST_HUMAN (464-797): 3.16e-33: 141: 9.44
+	Hs
		203190 KDM1A_HUMAN (1-852): 0: 936: 100.00		SYNJ1_HUMAN (2-318): 8.51e-09: 61.5: 8.49
+	Mm
		57189 SMRC2_MOUSE (5-300): 1.94e-57: 216: 15.14		CHD7_MOUSE (40-753): 1.1e-30: 132: 10.26
+	Hs
		1239571 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		KMT2C_HUMAN (5-646): 3.67e-10: 66.1: 7.94
+	Hs
		1056891 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		MDC1_HUMAN (24-492): 1.65e-09: 63.9: 13.03
+	Hs
		1056901 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		MDC1_HUMAN (24-492): 1.65e-09: 63.9: 13.03
+	Hs
		1056914 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		MDC1_HUMAN (24-492): 1.65e-09: 63.9: 13.03