Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A
Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 0.60 | 0.743 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32807901, 38580884, 17805299, 18573881, 26334721, 22653443 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, pull down, enzymatic study, anti tag coimmunoprecipitation, demethylase assay, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association, demethylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0002039 - p53 binding GO:0003682 - chromatin binding GO:0005634 - nucleus and 11 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
