HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: KLF3 (P57682)
Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2)
Gene: KLF3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	35140242, 23455924
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 345
+	Hs
		232373 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZN480_HUMAN (13-344): 1.81e-134: 395: 15.59
+	Hs
		232489 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZN436_HUMAN (84-344): 3.96e-106: 320: 20.07
+	Hs
		232532 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZNF71_HUMAN (13-120): 2.11e-23: 102: 9.17
+	Hs
		232349 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZFP28_HUMAN (11-122): 7.71e-23: 101: 7.08
+	Hs
		157868 AOFB_HUMAN (288-847): 8.85e-119: 371: 17.78		KLF11_HUMAN (256-343): 1.65e-28: 117: 65.91
+	Hs
		1032218 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		KLF1_HUMAN (254-343): 2.2e-36: 136: 71.11
+	Hs
		1032220 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		KLF1_HUMAN (254-343): 2.2e-36: 136: 71.11
+	Hs
		435141 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SP1_HUMAN (256-342): 6.19e-26: 110: 57.47
+	Hs
		435153 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SP1_HUMAN (256-342): 6.19e-26: 110: 57.47