HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Amino_oxidase~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 126
+	Hs
		232191 KDM1A_HUMAN (1-852): 0: 936: 100.00		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		232398 KDM1A_HUMAN (1-852): 0: 936: 100.00		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		232087 KDM1A_HUMAN (1-852): 0: 936: 100.00		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1087268 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		918526 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1129833 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		H2B2F_HUMAN (1-126): 3.9e-54: 167: 97.62
+	Hs
		1087279 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		1087316 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		1251596 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		707692 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		886169 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		H2B1D_HUMAN (1-126): 2.74e-53: 165: 100.00
+	Hs
		918539 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		918577 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1272926 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		H2B1L_HUMAN (1-126): 3.72e-52: 162: 97.62