Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 29568061, 36089195, 20389281, 31152129, 16956976, 16223729, 16140033, 16079794, 20228790
Identification Methods proximity labelling technology, enzymatic study, unspecified method, demethylase assay
Interaction Type physical association, direct interaction, association, demethylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Amino_oxidase~Histone
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032991 - protein-containing complex
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 852
Hs

1 136
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024