HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: CRTC1 (Q6UUV9)
CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)
Gene: CRTC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 634
+	Hs
		232559 KDM1A_HUMAN (1-852): 0: 936: 100.00		CHD7_HUMAN (9-561): 7.12e-15: 80.7: 12.28
+	Hs
		232444 KDM1A_HUMAN (1-852): 0: 936: 100.00		CIC_HUMAN (31-553): 6.06e-12: 71.4: 11.41
+	Hs
		203190 KDM1A_HUMAN (1-852): 0: 936: 100.00		SYNJ1_HUMAN (299-623): 1.74e-09: 63.3: 15.06
+	Hs
		1251639 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CHD7_HUMAN (9-561): 7.12e-15: 80.7: 12.28
+	Hs
		1272954 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CHD7_HUMAN (9-561): 7.12e-15: 80.7: 12.28
+	Hs
		1239571 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		KMT2C_HUMAN (27-599): 2.32e-09: 62.9: 8.10
+	Hs
		1272921 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CIC_HUMAN (31-553): 6.06e-12: 71.4: 11.41
+	Mm
		57189 SMRC2_MOUSE (5-300): 1.94e-57: 216: 15.14		CHD7_MOUSE (94-632): 2.4e-09: 62.9: 6.92
+	Dm
		1370310 Q9VVK2_DROME (266-497): 4.67e-26: 114: 19.84		Q9VLS7_DROME (55-605): 7.85e-09: 61: 10.51