HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: RCOR2 (Q8IZ40)
REST corepressor 2
Gene: RCOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 34079125, 34709266, 28420882, 24726434
Identification Methods proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Amino_oxidase~Myb_DNA-binding
Common GO terms GO:0005667 - transcription regulator complex
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0019899 - enzyme binding
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 852
Hs

1 523
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024