HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23455924
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0021987 - cerebral cortex development GO:0032991 - protein-containing complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 1164
+	Mm
		1169788 KDM1A_MOUSE (1-852): 0: 922: 97.30		TSC1_MOUSE (1-1164): 0: 695: 86.98
+	Hs
		232163 KDM1A_HUMAN (1-852): 0: 936: 100.00		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		232020 KDM1A_HUMAN (1-852): 0: 936: 100.00		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148185 KDM1A_HUMAN (1-852): 0: 936: 100.00		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		231989 KDM1A_HUMAN (1-852): 0: 936: 100.00		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Mm
		93560 KDM1A_MOUSE (1-852): 0: 922: 97.30		DESP_MOUSE (718-1164): 2.9e-13: 77.2: 10.89
+	Hs
		149083 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		149139 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78