HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: PF21B (Q96EK2)
PHD finger protein 21B
Gene: PHF21B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 852 Hs			1 531
+	Hs
		232572 KDM1A_HUMAN (1-852): 0: 936: 100.00		KDM5B_HUMAN (79-519): 1.17e-70: 247: 13.09
+	Mm
		1169717 KDM1A_MOUSE (1-852): 0: 922: 97.30		KDM5B_MOUSE (79-519): 4.61e-69: 243: 12.90
+	Mm
		1145012 KDM1A_MOUSE (1-852): 0: 922: 97.30		TIF1A_MOUSE (5-502): 5.67e-68: 238: 13.26
+	Mm
		1113374 KDM1A_MOUSE (1-852): 0: 922: 97.30		KDM5A_MOUSE (79-519): 3.35e-66: 235: 13.31
+	Hs
		232405 KDM1A_HUMAN (1-852): 0: 936: 100.00		PF21A_HUMAN (41-531): 1.26e-53: 194: 28.84
+	Mm
		1169606 KDM1A_MOUSE (1-852): 0: 922: 97.30		PF21A_MOUSE (41-531): 6.85e-54: 195: 29.21
+	Hs
		231945 KDM1A_HUMAN (1-852): 0: 936: 100.00		NSD2_HUMAN (87-515): 7.44e-41: 160: 12.72
+	Hs
		232170 KDM1A_HUMAN (1-852): 0: 936: 100.00		CHD4_HUMAN (301-481): 3.03e-37: 149: 20.51
+	Hs
		232586 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZMYD8_HUMAN (250-449): 2.18e-36: 146: 19.00
+	Hs
		232129 KDM1A_HUMAN (1-852): 0: 936: 100.00		CHD3_HUMAN (167-481): 8.3e-35: 142: 15.04
+	Hs
		232139 KDM1A_HUMAN (1-852): 0: 936: 100.00		TIF1B_HUMAN (113-501): 1.53e-33: 137: 16.58
+	Mm
		1161068 KDM1A_MOUSE (1-852): 0: 922: 97.30		CHD4_MOUSE (301-481): 1.85e-37: 149: 20.51
+	Mm
		1112509 KDM1A_MOUSE (1-852): 0: 922: 97.30		Q3UH28_MOUSE (288-449): 8.51e-32: 132: 19.14
+	Hs
		232442 KDM1A_HUMAN (1-852): 0: 936: 100.00		PHF12_HUMAN (337-405): 5.06e-13: 74.1: 35.62
+	Ce
		104632 KDM1A_CAEEL (182-831): 1.14e-174: 525: 27.60		LE418_CAEEL (136-504): 5.29e-35: 142: 13.64
+	Hs
		782365 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		KDM5C_HUMAN (78-518): 6.19e-66: 234: 13.45
+	Hs
		1059749 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CHD4_HUMAN (301-481): 3.03e-37: 149: 20.51
+	Hs
		1018598 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CHD3_HUMAN (167-481): 8.3e-35: 142: 15.04
+	Mm
		956818 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		TIF1B_MOUSE (113-501): 6.61e-32: 132: 15.56
+	Mm
		956835 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		BAZ1B_MOUSE (355-404): 4.62e-12: 71: 35.85