HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: IFT74 (Q96LB3)
Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2)
Gene: IFT74

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 600
+	Hs
		232163 KDM1A_HUMAN (1-852): 0: 936: 100.00		DCTN1_HUMAN (10-416): 1.26e-29: 127: 15.22
+	Hs
		232020 KDM1A_HUMAN (1-852): 0: 936: 100.00		MYH9_HUMAN (40-497): 4.47e-16: 84.3: 8.52
+	Hs
		148185 KDM1A_HUMAN (1-852): 0: 936: 100.00		CTRO_HUMAN (101-590): 8.63e-13: 73.9: 14.98
+	Hs
		231989 KDM1A_HUMAN (1-852): 0: 936: 100.00		DESP_HUMAN (64-554): 2.32e-12: 72.4: 14.65
+	Mm
		93560 KDM1A_MOUSE (1-852): 0: 922: 97.30		DESP_MOUSE (64-554): 4.52e-13: 74.7: 14.26
+	Hs
		1078874 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		ITSN1_HUMAN (129-513): 6.26e-14: 77.4: 14.47
+	Hs
		149083 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		CTRO_HUMAN (101-590): 8.63e-13: 73.9: 14.98
+	Hs
		149139 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CTRO_HUMAN (101-590): 8.63e-13: 73.9: 14.98