HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: UBP28 (Q96RU2)
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Gene: USP28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	24075993, 31833203
Identification Methods	affinity chromatography technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0034644 - cellular response to UV
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 1077
+	Hs
		232266 KDM1A_HUMAN (1-852): 0: 936: 100.00		UBP34_HUMAN (151-417): 5.88e-65: 243: 24.64
+	Hs
		232395 KDM1A_HUMAN (1-852): 0: 936: 100.00		USP9X_HUMAN (136-452): 1.14e-61: 233: 18.33
+	Hs
		232396 KDM1A_HUMAN (1-852): 0: 936: 100.00		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Mm
		1149450 KDM1A_MOUSE (1-852): 0: 922: 97.30		UBP7_MOUSE (547-839): 6.59e-23: 108: 18.91
+	Hs
		232595 KDM1A_HUMAN (1-852): 0: 936: 100.00		UBP22_HUMAN (428-654): 3.12e-11: 69.2: 18.42
+	Mm
		1149448 SMRC2_MOUSE (5-300): 1.94e-57: 216: 15.14		UBP7_MOUSE (547-839): 6.59e-23: 108: 18.91
+	Hs
		1251594 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Hs
		1272915 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13