HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: HM20B (Q9P0W2)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35)
Gene: HMG20B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	26186194, 28514442, 12032298, 33961781, 12493763, 34709266, 16140033, 16079794, 21258344
Identification Methods	affinity chromatography technology, biochemical, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 852 Hs			1 317
+	Mm
		1169804 KDM1A_MOUSE (1-852): 0: 922: 97.30		HM20B_MOUSE (1-317): 2.55e-76: 238: 93.69
+	Hs
		232530 KDM1A_HUMAN (1-852): 0: 936: 100.00		HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35
+	Mm
		1169785 KDM1A_MOUSE (1-852): 0: 922: 97.30		HM20A_MOUSE (25-313): 3.31e-55: 184: 48.45
+	Hs
		231945 KDM1A_HUMAN (1-852): 0: 936: 100.00		NSD2_HUMAN (2-282): 1.75e-30: 123: 13.01
+	Hs
		232040 KDM1A_HUMAN (1-852): 0: 936: 100.00		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Mm
		675607 KDM1A_MOUSE (1-852): 0: 922: 97.30		HMGB2_MOUSE (64-137): 5.59e-10: 60.2: 30.26
+	Zm
		9154 A0A1D6K7D0_MAIZE (103-840): 2.57e-171: 543: 29.25		A0A1D6EUM9_MAIZE (57-163): 3.67e-29: 111: 28.70
+	Hs
		818822 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SOX9_HUMAN (4-181): 2.99e-29: 118: 17.26
+	Hs
		818829 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SOX9_HUMAN (4-181): 2.99e-29: 118: 17.26
+	Hs
		1251597 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SMCE1_HUMAN (74-315): 3.79e-29: 117: 21.18
+	Hs
		1272916 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SMCE1_HUMAN (74-315): 3.79e-29: 117: 21.18
+	Hs
		996811 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SSRP1_HUMAN (31-233): 9.74e-28: 115: 16.91
+	Mm
		222670 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		SMCE1_MOUSE (74-315): 1.95e-27: 112: 21.18
+	Mm
		818694 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		SOX2_MOUSE (37-153): 1.1e-26: 109: 26.50
+	Mm
		956815 SMRC1_MOUSE (34-300): 3.24e-58: 218: 17.65		Q60I23_MOUSE (37-153): 5.51e-27: 109: 26.50
+	Mm
		1142003 SMRC2_MOUSE (5-300): 1.94e-57: 216: 15.14		Q60I23_MOUSE (37-153): 5.51e-27: 109: 26.50
+	Hs
		818277 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		818323 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		1251615 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		SOX7_HUMAN (32-182): 2.11e-24: 103: 20.73
+	Hs
		1272928 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		SOX7_HUMAN (32-182): 2.11e-24: 103: 20.73