Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A
Interactor 2: NR2E1 (Q9Y466)
Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (hTll)
Gene: NR2E1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.76 | 0.60 | 0.676 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18391013, 28420882, 36321378 |
| Identification Methods | affinity chromatography technology, pull down, anti bait coimmunoprecipitation, mass spectrometry study of hydrogen/deuterium exchange, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0002052 - positive regulation of neuroblast proliferation GO:0005654 - nucleoplasm GO:2000648 - positive regulation of stem cell proliferation |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
