HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 551
+	Hs
		232971 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Hs
		1084479 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		1130319 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		1130201 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		Q6IQ30_HUMAN (81-517): 3.07e-29: 124: 14.00
+	Hs
		90116 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		D6REX3_HUMAN (120-488): 2.19e-28: 122: 15.14
+	Hs
		516547 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		867104 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		SC24C_HUMAN (233-440): 1.79e-12: 72.2: 17.05
+	Hs
		1130521 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59