HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: SPDLY (Q96EA4)
Protein Spindly (hSpindly) (Arsenite-related gene 1 protein) (Coiled-coil domain-containing protein 99) (Rhabdomyosarcoma antigen MU-RMS-40.4A) (Spindle apparatus coiled-coil domain-containing protein 1)
Gene: SPDL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 605
+	Hs
		232778 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37
+	Hs
		232794 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		551732 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37
+	Hs
		254486 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		ROCK2_HUMAN (2-601): 2.07e-45: 175: 18.70
+	Hs
		724862 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		725175 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		433184 ERBIN_HUMAN (637-806): 2.73e-09: 64.3: 26.86		LAMB1_HUMAN (4-230): 1.14e-12: 73.6: 11.98