HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 2240
+	Hs
		233027 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		232742 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		ANR17_HUMAN (1108-2079): 3.68e-42: 173: 12.34
+	Hs
		1130521 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		DIDO1_HUMAN (1-2240): 0: 732: 100.00
+	Hs
		1130774 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		257621 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		ANR17_HUMAN (1108-2079): 3.68e-42: 173: 12.34
+	Hs
		1075109 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		TCEA2_HUMAN (577-816): 6.11e-40: 153: 19.20
+	Hs
		92119 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		NACAM_HUMAN (6-1024): 1.9e-22: 108: 10.86
+	Hs
		867104 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		SC24C_HUMAN (1537-1898): 1.52e-16: 88.6: 19.74
+	Hs
		3594 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		A0A140VK53_HUMAN (6-1279): 6.35e-14: 80.3: 8.36