HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: RPAP3 (Q9H6T3)
RNA polymerase II-associated protein 3
Gene: RPAP3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27880917, 33397691
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 665
+	Hs
		232821 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		PPP5_HUMAN (131-251): 3.46e-14: 77.4: 32.23
+	Hs
		1130595 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		RPAP3_HUMAN (1-665): 1.27e-121: 378: 100.00
+	Hs
		175307 SHOC2_HUMAN (628-1094): 2.39e-24: 112: 27.84		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		174950 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		685036 LRC40_HUMAN (691-1141): 7.56e-25: 113: 25.00		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		684799 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		66551 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		A8K690_HUMAN (100-594): 1.35e-19: 94.7: 14.23
+	Hs
		297066 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		TOM70_HUMAN (36-379): 1.61e-15: 82.2: 16.52
+	Hs
		1130486 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		DNJC7_HUMAN (42-289): 2.69e-15: 81.2: 16.11
+	Hs
		858664 LRRC1_HUMAN (896-1143): 8.91e-09: 62: 28.74		PPP5_HUMAN (131-251): 3.46e-14: 77.4: 32.23