HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: Q9P1S2 (Q9P1S2)
HDCMD34P
Gene: Q9P1S2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19615732
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 165
+	Hs
		232821 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		PPP5_HUMAN (3-161): 1.41e-37: 136: 14.72
+	Hs
		233024 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		SGT1_HUMAN (3-165): 1.1e-36: 131: 93.87
+	Hs
		1172971 PHLP2_HUMAN (469-1717): 0: 884: 53.15		SGT1_HUMAN (3-165): 1.1e-36: 131: 93.87
+	Dm
		1364726 SUR8_DROME (638-866): 3.65e-36: 149: 21.30		Q9VH81_DROME (3-161): 2.9e-33: 124: 14.02
+	Hs
		73181 LRC40_HUMAN (691-1141): 7.56e-25: 113: 25.00		B4DYC6_HUMAN (35-165): 1.96e-41: 141: 68.70
+	Hs
		73193 SHOC2_HUMAN (628-1094): 2.39e-24: 112: 27.84		B4DYC6_HUMAN (35-165): 1.96e-41: 141: 68.70
+	Hs
		1334127 LRC40_HUMAN (691-1141): 7.56e-25: 113: 25.00		SGT1_HUMAN (3-165): 1.1e-36: 131: 93.87
+	Hs
		1357816 SHOC2_HUMAN (628-1094): 2.39e-24: 112: 27.84		SGT1_HUMAN (3-165): 1.1e-36: 131: 93.87
+	Hs
		66537 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		A8K5T7_HUMAN (3-165): 8.98e-37: 131: 93.87
+	Hs
		73173 LRRC1_HUMAN (896-1143): 8.91e-09: 62: 28.74		B4DYC6_HUMAN (35-165): 1.96e-41: 141: 68.70
+	Hs
		858664 LRRC1_HUMAN (896-1143): 8.91e-09: 62: 28.74		PPP5_HUMAN (3-161): 1.41e-37: 136: 14.72
+	Hs
		1301469 ERBIN_HUMAN (637-806): 2.73e-09: 64.3: 26.86		SGT1_HUMAN (3-165): 1.1e-36: 131: 93.87
+	Hs
		1312326 LRRC1_HUMAN (896-1143): 8.91e-09: 62: 28.74		SGT1_HUMAN (3-165): 1.1e-36: 131: 93.87
+	Hs
		175307 SHOC2_HUMAN (628-1094): 2.39e-24: 112: 27.84		OGT1_HUMAN (3-153): 1.8e-17: 80.3: 10.60
+	Hs
		685036 LRC40_HUMAN (691-1141): 7.56e-25: 113: 25.00		STIP1_HUMAN (12-90): 1.09e-11: 63.8: 22.79
+	Hs
		174950 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		OGT1_HUMAN (3-153): 1.8e-17: 80.3: 10.60
+	Hs
		672847 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		CDC27_HUMAN (2-143): 5.07e-14: 70.3: 15.49
+	Hs
		66551 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		A8K690_HUMAN (12-90): 9.97e-12: 63.8: 22.79
+	Hs
		684799 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		STIP1_HUMAN (12-90): 1.09e-11: 63.8: 22.79