HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 2896
+	Hs
		232971 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		DIDO1_HUMAN (88-631): 5.4e-37: 156: 16.09
+	Hs
		1130774 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		PRC2C_HUMAN (1-2896): 0: 771: 100.00
+	Hs
		1130521 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		DIDO1_HUMAN (88-631): 5.4e-37: 156: 16.09
+	Hs
		92119 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		NACAM_HUMAN (47-1172): 1.56e-31: 138: 8.12
+	Hs
		3594 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		A0A140VK53_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Dm
		1370303 TOLL6_DROME (732-1169): 4.53e-12: 73.6: 22.57		Q9VLS7_DROME (1208-2548): 1.93e-23: 111: 9.16
+	Dm
		56245 A1ZBR2_DROME (693-1147): 7.74e-10: 66.2: 23.16		Q9VLS7_DROME (1208-2548): 1.93e-23: 111: 9.16